Experts in the News

In a recent paper in the Proceedings of the National Academy of Sciences, School of Biological Sciences Associate Professor William Ratcliff and Emma Bingham, student in the Interdisciplinary Graduate Program in Quantitative Biosciences, put forward a brand new idea, which they tested in a computational model. Bingham and Ratcliff suggest that the way prokaryotic and eukaryotic genomes respond to population size may make or break their chances of evolving multicellularity. It’s a fascinating hypothesis, and if further work bears it out, it could fundamentally change how scientists conceive of this transition and challenge a key assumption they make about evolutionary forces.

Despite being chock-full of hardcore science, 3 Body Problem, a television series released on 21 March by the streaming service Netflix, has been a hit with audiences. The story follows five young scientists who studied together at the University of Oxford, UK, as they grapple with mysterious deaths, particle-physics gone awry, and aliens called the San-Ti who have their sights set on Earth. But how much of the science in the sci-fi epic reflects reality, and how much is wishful thinking? To find out, Nature spoke to three real-world scientists, including School of Chemistry & Biochemistry professor Younan Xia.

Regular exercise promotes whole-body health and prevents disease, but the underlying molecular mechanisms are incompletely understood. Here, the Molecular Transducers of Physical Activity Consortium – whose researchers include Regents' Professor and Vasser-Woolley Chair in Bioanalytical Chemistry Facundo Fernández – profiled the temporal transcriptome, proteome, metabolome, lipidome, phosphoproteome, acetylproteome, ubiquitylproteome, epigenome and immunome in whole blood, plasma and 18 solid tissues in male and female Rattus norvegicusover eight weeks of endurance exercise training. The data and analyses presented in the study serve as valuable resources for understanding and exploring the multi-tissue molecular effects of endurance training.

Estimating fire emissions prior to the satellite era is challenging because observations are limited, leading to large uncertainties in the calculated aerosol climate forcing following the preindustrial era. This challenge further limits the ability of climate models to accurately project future climate change. In this study, researchers reconstruct a gridded dataset of global biomass burning emissions from 1750 to 2010 using inverse analysis that leveraged a global array of 31 ice core records of black carbon deposition fluxes, two different historical emission inventories as a priori estimates, and emission-deposition sensitivities simulated by the atmospheric chemical transport model GEOS-Chem. The study’s researchers include Bingqing Zhang, Takamitsu Ito, and Pengfei Liu of the School of Earth and Atmospheric Sciences.

Heterotrophic activity, primarily driven by sulfate-reducing prokaryotes, has traditionally been linked to nitrogen fixation in the root zone of coastal marine plants, leaving the role of chemolithoautotrophy in this process unexplored. The researchers show that sulfur oxidation coupled to nitrogen fixation is a previously overlooked process providing nitrogen to coastal marine macrophytes. In their study, they recovered 239 metagenome-assembled genomes from a salt marsh dominated by the foundation plant Spartina alterniflora, including diazotrophic sulfate-reducing and sulfur-oxidizing bacteria. Based on the findings, the researchers propose that the symbiosis between S. alterniflora and sulfur-oxidizing bacteria is key to ecosystem functioning of coastal salt marshes. The study's co-authors include School of Biological Sciences researchers: Jose Louis Rolando, Maxim Kolton, Tianze Song, Roth Conrad, Y. Liu, P. Pinamang, Professor and Associate Chair of Research Joel Kostka, and Professor Kostas Konstantinidis. (Konstantinidis is also professor in the School of Civil and Environmental Engineering.)

Robotics engineers have worked for decades, using substantial funding, to create robots that can walk or run with the ease of animals. Despite these efforts, today’s robots still cannot match the natural abilities of many animals in terms of endurance, agility, and robustness. Seeking to understand and quantify this disparity, an interdisciplinary team of scientists and engineers from top research institutions, including Dunn Family Associate Professor at the School of Physics and the School of Biological Sciences Simon Sponberg, conducted a comprehensive study to compare various aspects of robotic systems designed for running with their biological counterparts. (This also appeared at The Jerusalem Post and SciTechDaily.)

A group of researchers at the Georgia Institute of Technology have created the world’s first functional semiconductor made from graphene, a development that could lead to advanced electronic devices and quantum computing applications. Seen as the building block of electronic devices, semiconductors are essential for communications, computing, healthcare, military systems, transportation and countless other applications. Semiconductors are typically made from silicon, but this material is reaching its limit in the face of increasingly faster computing and smaller electronic devices, according to the Georgia Tech research team who published their findings in Nature earlier this year. In a drive to find a viable alternative to silicon, Walter de Heer, Regents' Professor in the School of Physics, led a team of researchers based in Atlanta, Georgia and Tianjin, China to produce a graphene semiconductor that is compatible with microelectronics processing methods.

It’s possible for volcanoes to have a short-term impact on the climate – including global temperature cooling – due to the gases they inject high into the upper atmosphere. But Mount Ruang’s influence on the climate will likely be minimal, according to Greg Huey, professor and chair of the School of Earth and Atmospheric Sciences. And the day-to-day weather conditions near Mount Ruang in Indonesia – things like temperature, clouds and rain – probably won’t be influenced by the volcano for long, Huey told CNN. “The ash itself is short-lived in the atmosphere because it’s heavy, it’s big and it tends to settle out quickly,” Huey told CNN. It’s the gases that are able to reach much higher in the atmosphere. (This story also appeared at WRAL.)

"A dog is a man's best friend," the old saying goes. Can the same soon be said of robot dogs? This summer, a group of scientists including alumna Feifei Qian (M.S. PHYS 2011, Ph.D. ECE 2015) and School of Earth and Atmospheric Sciences assistant professor Frances Rivera-Hernández, will travel to Oregon's snow-capped Mt. Hood to train a dog-shaped robot named Spirit how to walk. The slopes of Mt. Hood are strewn with volcanic rocks and sprinkled with glaciers, a rugged environment that researchers think resembles the moon — which Spirit is being prepared to eventually explore. (This story also appeared at BBC, Reuters, Sharjah 24. and TAG 24).

In a new study, published in GEN Biotechnology titled, “Changes in Gene Network Interactions in Breast Cancer Onset and Development,” researchers from the School of Biological Sciences and the Integrated Cancer Research Center (Zainab Arshad, Stephen N. Housley, Kara Keun Lee, and John F. McDonald) have identified differential gene-network changes characteristic of the three most prevalent molecular subtypes of breast cancer, Luminal A, Luminal B, and the highly metastatic Basal-like subtype. In contrast to previous studies, the authors expanded their analysis beyond genes differentially expressed between normal and cancer samples, as differential gene expression may not be a prerequisite for changes in gene-gene interactions. (This story also appeared at Medical Xpress and Mirage News.)

In an opinion published in the May 2024 edition of APSNews, School of Physics Professor Andrew Zangwill reflects on the debate on the boundaries of physics and its impact on the discipline. Zangwill states “for more than a century, physicists have been drawing and redrawing the borders around the field, embracing and rejecting subfields along the way.”

The stars aligned to give a Georgia Tech undergraduate student and an alum the moment of a lifetime during the recent solar eclipse. Corinne Hill is currently majoring in physics with a concentration in astrophysics. Nathaniel Greve graduated in 2023 with a degree in computer science. The couple met in 2021 when they both played alto saxes in the Georgia Tech marching band. After being unable to experience totality in 2017, Greve said the pair made plans to go to Wapakoneta, Ohio, for 2024′s eclipse. Hill’s friends in the Astronomy Club went to the Ozarks to experience the eclipse, but Hill agreed to go to Ohio instead.