Experts in the News

In a rhythm that’s pulsed through epochs, a river’s plume carries sediment and nutrients from the continental interior into the ocean, a major exchange of resources from land to sea. More than 6,000 rivers worldwide surge freshwater into oceans, delivering nutrients, including nitrogen and phosphorus, that feed phytoplankton, generating a bloom of life that in turn feeds progressively larger creatures. They may even influence ocean currents in ways researchers are just starting to understand. But today, in rivers around the world, humans are altering this critical phenomenon. In many places, the culprit is a dam. Researchers led by Annalisa Bracco, professor in the School of Earth and Atmospheric Sciences, investigated these dynamics in a study of the plume created by the Mekong River, the 12th-longest river in the world. The study found that current and proposed Mekong River dams will dramatically reduce its annual mean flow, its seasonal cycle, and sediment loading. The scientists argue that a reduced productivity of the offshore water of the South China Sea along the pathway of the summer jet may be an undesirable outcome as well. Other EAS researchers in the study are Xiyuan Zeng, graduate student, and Filippos Tagklis, postdoctoral scholar. 

Model systems are a cornerstone of microbiology. However, despite microbiology’s heavy reliance on laboratory models, these systems are typically not analyzed systematically to improve their relevance. This limitation is a primary challenge to understand microbes’ physiology in natural environments. This study, which includes members of Georgia Tech's Center for Microbial Dynamics and Infection (CMDI), provides a proof of concept for generalizable approaches for model improvement using transcriptomic data of the pathogen Pseudomonas aeruginosa from sputum of patients with cystic fibrosis. The study's researchers include Marvin Whiteley, professor in the School of Biological Sciences, Georgia Tech Bennie H. and Nelson D. Abell Chair in Molecular and Cellular Biology, Georgia Research Alliance Eminent Scholar, and Co-Director, Emory-Children’s Cystic Fibrosis Center; Other School of Biological Sciences and CMDI researchers include Gina R. Lewin, postdoctoral scholar, and research scientists Daniel Cornforth and Francis Diggle. 

This feature article is a written version of a lecture that Dan Margalit, professor in the School of Mathematics, gave at the 2022 Joint Mathematical Meetings of the American Mathematical Society (AMS). The Society established the Maryam Mirzakhani Lecture in 2018 to honor the memory of Mirzakhani, the first woman and first Iranian to win the Fields Medal, one of the highest honors in math. Margalit writes that on a basic level, Mirzakhani’s work centers around the geometry of surfaces, as understood through their simple curves: "Starting from this humble-seeming topic, Mirzakhani made surprising and sweeping connections between numerous fields of mathematics, including algebraic geometry, Teichmüller theory, moduli spaces, dynamics, homogeneous spaces, symplectic geometry, and billiards."

More than 40 partners  —  including Georgia Tech and other higher education institutions, non-profits, corporations, community groups, researchers and arts organizations  —  have joined together to collaborate on climate change solutions at The New York Climate Exchange. Georgia Tech is also a leading partner of the Ocean Visions – UN Decade Collaborative Center for Ocean-Climate Solutions, an international center headquartered at the Georgia Aquarium that aims to co-design, develop, test, fund, and deliver scalable and equitable ocean-based solutions to reduce the effects of climate change and build climate-resilient marine ecosystems and coastal communities. Championed at Georgia Tech by Susan Lozier, dean and Betsy Middleton and John Clark Sutherland Chair in the College of Sciences, the Center also supports opportunities to accelerate ocean-based carbon dioxide removal research and advance sustainable ocean economies.

Karla Haack, who received her Ph.D. in 2009 in molecular biology from the School of Biological Sciences, and is a member of the College of Sciences Advisory Board, is one of five new 2023-2024 member leaders of the American Physiological Society (APS). Haack, a medical writer for Merck, was elected as a councilor during the recent APS Summit in Long Beach, California. Prior to joining Merck in 2021, Haack taught anatomy, physiology and pathophysiology courses at Kennesaw State University (KSU) in Georgia. Haack completed her postdoctoral research at the University of Nebraska Medical Center.

Blinking is crucial for the eye. It's how animals clean their eyes, protect them, and even communicate. But how and why did blinking originate? Researchers at the Georgia Institute of Technology, Seton Hill University, and Pennsylvania State University studied the mudskipper, an amphibious fish that spends most of its day on land, to better understand why blinking is a fundamental behavior for life on land. By comparing the anatomy and behavior of mudskippers to the fossil record of early tetrapods, the researchers argue that blinking emerged in both groups as an adaptation to life on land. One  of the researchers, Brett Aiello, an assistant professor of biology at Seton Hill University, is a former postdoctoral fellow in the Agile Systems Lab at Georgia Tech. Saad Bhamla, assistant professor in the School of Chemical and Biomolecular Engineering, is a co-author of the study.  (This story is also covered in Earth.com, SciTechDaily and the Latrobe Bulletin.) 

Yeast are carb lovers, sustaining themselves by fermenting sugars and starches from sources such as dough, grapes, and grains, with bread, wine, and beer as happy byproducts. Now, researchers have made one type of yeast a little less dependent on carbs by enabling it to use light as energy. The work, reported last week on the preprint server bioRxiv, is “the first step in more complex modes of engineering artificial photosynthesis,” says Magdalena Rose Osburn, a geobiologist at Northwestern University who was not involved in the research. The study's four co-authors are all with the School of Biological Sciences and Georgia Tech's Center for Microbial Dynamics and Infection: Ph.D. student Autumn Peterson, senior scientist and grant writer Carina Baskett; Will Ratcliff, associate professor and co-director of the Interdisciplinary Ph.D. in Quantitative Biosciences; and research scientist Anthony Burnetti. 

Fermented foods like kimchi have been an integral part of Korean cuisine for thousands of years. Today, most kimchi is made through mass fermentation in glass, steel, or plastic containers, but it’s long been claimed that the highest quality kimchi is fermented in traditional handmade clay jars called onggi. David Hu, a professor in the School of Biological Sciences and the Georgia W. Woodruff School of Mechanical Engineering, used fluid dynamics to prove how onggi make kimchi taste so good. The results were published in the Journal of the Royal Society Interface. (This story was also covered in list23, SFGate, The Washington Post, Scientific American, Gulf News, Yahoo!News, Ars Technica and Technology Networks.)

Life depends on molecular machines made of proteins that interact with each other to form functional complexes. Researchers need accurate descriptions of protein-protein interactions to understand molecular biosystems, but obtaining such descriptions is very challenging, especially for theoretical approaches. Generalizing AlphaFold 2, a powerful deep learning algorithm for predicting protein structures from sequence, researchers at Georgia Institute of Technology and Oak Ridge National Laboratory proposed a computational approach, AF2Complex, to not only predict the atomic structural models of interacting proteins, but also to predict whether multiple proteins interact, even if they experience transient interactions that are difficult to capture experimentally. The Georgia Tech School of Biological Sciences researchers are Mu Gao, senior research scientist, and Jeffrey Skolnick, Regents' Professor; Mary and Maisie Gibson Chair & GRA Eminent Scholar in Computational Systems Biology. (Their study is funded in part by the U.S. Dept. of Energy and the National Institutes of Health.)

Two prominent origin-of-life chemists have published a new hypothesis for how the first sugars — which were necessary for life to evolve — arose on the early Earth. In a paper in the journal Chem, chemists from Scripps Research and the Georgia Institute of Technology propose that key sugars needed for making early life forms could have emerged from reactions involving glyoxylate (C2HO3–), a relatively simple chemical that plausibly existed on the Earth before life evolved. Charles Liotta, Regents' Professor Emeritus in the School of Chemistry and Biochemistry and the School of Chemical and Biomolecular Engineering, is one of the study's authors. (This study was also covered in Astrobiology and Mirage News.)

The 2019 release of the first image of a black hole, captured by the Event Horizon Telescope (EHT), was hailed as a significant scientific achievement. But truth be told, it was a bit blurry — or, as one astrophysicist involved in the effort called it, a "fuzzy orange donut." Scientists on Thursday unveiled a new and improved image of this black hole — a behemoth at the center of a nearby galaxy — mining the same data used for the earlier one but improving its resolution by employing image reconstruction algorithms to fill in gaps in the original telescope observations. The use of machine learning to improve the photo is detailed in a study in the Astrophysical Journal Letters. Two professors in the School of Physics who are EHT founding members — Feryal Ozel, who is also school chair, and Dimitrios Psaltis — are co-authors of the study. (This story was also covered in Space Daily, ScienceDaily and the Calgary Herald.)

This story about an AI enhancement of the famous 2018 photo of the first-ever image of a black hole — captured by the Event Horizon Telescope featuring EHT founding members and School of Physics professors Feryal Ozel (also school chair) and Dimitrios Psaltis — is also covered in Scientific American, Ars Technica, The Washington Post, Phys.org, NPR, Sky News, MSN, USA Today, Yahoo!News, CBS News, Space.com, The Associated Press,   LiveScience, Smithsonian Magazine, Economic Times, Voice of America News, and UK Daily Mail.